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ICP-MS Analysis The concentrations of 26 elements (Ag, Al, As, Ba, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Mg, Mn, Mo, Na, Ni, Pb, Sb, Se, Th, Tl, U, V, and Zn) were determined in a subsample of each paper by inductively coupled plasma mass spectrometry as follows

& Fussell, J
In short then he seems to be saying that if you take just one shot of this highly addictive drug (after which you will almost certainly become addicted) then that first, initial dose might somehow provide some kind of benefit, perhaps in concentration (Id dispute even that flimsy suggestion)

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Inhal Toxicol 20:11791189 Marchand M, Brossard P, Merdjan H, Lama N, Weitkunat R, Ldicke F (2017) Nicotine population pharmacokinetics in healthy adult smokers: a retrospective analysis
