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DOI: Published: Publisher Name: Springer, New York, NY Print ISBN: 978-1-4939-3473-7 Online ISBN: 978-1-4939-3474-4 eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences Keywords Addiction Animal Models Acetylcholine Alcohol consumption CHRNA4 gene Conditioned place preference (CPP) Depression Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Dopamine (DA) system Ion Channels Interpeduncular nucleus (IPN) Locomotor sensitization Long-term potentiation (LTP) Medium spiny neurons (MSNs) Medial habenula (MHb) Nicotine addiction Nucleus Accumbens (NAc) Nicotinic Acetylcholine Receptors (nAChRs) Receptor Desensitization Obsessive compulsive disorder (OCD) Prepulse-inhibition Psychiatric disorders Schizophrenia Self-administration model Smoking Substance use disorders Tobacco Ventral tegmental area (VTA)

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