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Major Driver: Demand in regions where such products remain legal

It also increases susceptibility to inflammation, causing hair to die and shorten its life cycle

Observed outcomes show that dogs and cats serve as effective sentinels for SHS exposure, and also reveal that they accumulate nicotine metabolites, particularly cotinine, in biological matrices such as urine, serum, fur, and even amniotic fluid, which may adversely affect their health 40-42

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