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it is also produced in the Eastern United States (mostly in Florida, Kentucky, Tennessee, and Virginia) and in the Mediterranean countries of Italy, Greece, Spain (in the Canary Islands), and Turkey, and to a lesser degree in Indonesia and the Philippines of Southeast Asia

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Research shows that aerosol from e-cigarettes can contain harmful chemicals, including nicotine, ultra-fine particles that can be inhaled deep into the lungs, flavoring such as diacetyl, which is a chemical linked to a serious lung disease, she said

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The battery output voltage significantly affects the concentration of carbonyl compounds in the e-cigarette aerosol, and high-voltage e-cigarettes may expose users to high levels of carbonyl compounds