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Michael Fiore, a tobacco researcher at the University of Wisconsin, called the FDAs new approach a potential game-changer. Asked whether smokers would rise up in protest, Fiore said they were likely to welcome a chance to be free of their addiction

Philip Pape: 16:30 And, probably most importantly, the 20s marked the moment when weight became seen as something completely under individual control, this calorie counting that Peters came up with

[50:27] So we're just going to spread it out

Oxford: Wiley-Blackwell

This isoform switch is well observed during T cell activation: antigen-nave T cells express CD45RA whereas activated/memory T cells express CD45RO 19