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These data suggest that the geographic overlap of high TB burden and intense tobacco use is more than accidental

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At clinical concentrations, pretomanid does not inhibit major CYP isoenzymes, including CYP1A2, CYP2C8, CYP2C9, CYP2C19 or CYP2D6, and does not induce CYP2C9 or CYP3A4, limiting the potential for DDI trough CYPs

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Signs of PAD : Pain or cramping in your legs and feet during activity, known as claudication

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Even in 2026, tobacco taxes and levies remain high, leading to further price increases in retail

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doi: 10.3390/toxics10070382

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