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Description
These data suggest that the geographic overlap of high TB burden and intense tobacco use is more than accidental

At clinical concentrations, pretomanid does not inhibit major CYP isoenzymes, including CYP1A2, CYP2C8, CYP2C9, CYP2C19 or CYP2D6, and does not induce CYP2C9 or CYP3A4, limiting the potential for DDI trough CYPs

Signs of PAD : Pain or cramping in your legs and feet during activity, known as claudication
Even in 2026, tobacco taxes and levies remain high, leading to further price increases in retail

doi: 10.3390/toxics10070382
