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Most restrictive policies such as the ban on e-cigarettes appear to reduce e-cigarette use among the youth

This amounted to what Hajek called extremely large doses of nicotine. At the end of the three months, Tang found DNA damage in the hearts, lungs and bladders of mice exposed to the vapours that was not evident in a control group of animals that breathed filtered air

1 2 "Electronic cigarettes and vaping: a new challenge in clinical medicine and public health

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"Its toll will remain substantial without more concerted policy initiatives, policy compliance and enforcement, and sustained political will to offset commercial interests." The pace of progress in combatting smoking has so far been varied across countries and demographics, with researchers suggesting that efforts to reduce smoking could be hindered as tobacco companies target growing populations in developing economies