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Within the cohort of 92 patients where anti-tumor necrosis factor (TNF) therapy was ceased following remission and maintenance antimetabolite therapy continued, active smoking was identified as a risk factor for relapse (HR, 1.91

Nicotine is also a drug that changes your brain chemistry, explains Humberto Choi, MD, a board-certified pulmonologist at the Cleveland Clinic

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Other studies suggest that the positive health claims in cigarette advertising made during this period might have had an indirect negative effect on tobacco consumption by giving the impression that protection was needed, thereby reinforcing the health scare (IOM 2001)

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