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CCAT1 is highly expressed in inflammatory bowel disease patients and in colorectal cancer cells

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Clinical and experimental studies implicate IL-6 in the progression of cancers [11] and CVDs, including hypertension, atherosclerosis, aortic and thoracic aneurysms, cardiac fibrosis, aortic dissection, cardiomyopathy, heart failure, and ischemic stroke [40, 41]

USA 109 , 38263831 (2012)

Cancer immunotherapy using checkpoint blockade