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ENDS have the potential to reduce harm among adult cigarette smokers who have experienced difficulty quitting, as the aerosol from ENDS "contains fewer numbers and lower levels of most toxicants than does smoke from combustible tobacco cigarettes." 174 Yet the data are complex regarding the effectiveness of ENDS as a harm reduction or cessation tool for adults who smoke cigarettes

By the end of 2002, 19 states had excise taxes exceeding 50 cents per pack, and 5 states collected $1.00 per pack or greater

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In many cases, these regulations prohibit liquor manufacturers from selling products directly to retailers or consumers, and distributors must be used to store and sell alcohol at the wholesale level