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Table S1) [14, 15, 1724, 3842]

Anxiety, Restlessness, and Panic Nicotines stimulating effects can mimic anxiety symptoms - a racing heart, shortness of breath, and tension

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Symptoms seen in males: Burning sensation or itching in the penis area Discharge from the penis (also known as a drip) Pain around lower abdomen/pelvis area Sores, bumps, warts or blisters on the penis, anus or in the mouth Burning sensation and pain during urination or during bowel movements Increased frequency of urination Swelling in scrotum/testes Sore, swollen lymph nodes in the groin area Symptoms seen in females: The most common symptom is change in the vaginal discharge that may have a bad odour or may be discoloured

Hilleman DE, Mohiuddin SM, Delcore MG (1994)