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Airway mucus and asthma: the role of MUC5AC and MUC5B

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After 2 weeks of usual treatment with a 21-mg patch, participants who fail to quit smoking (target n = 400) will be randomized to receive escalating doses of a nicotine patch vs matching placebo patches for an additional 10 weeks or up to a maximum dose of 84 mg per day

Given similar declines in the early years, a positive relationship exists between adult and youth smoking in the time-series model, but the relationship does not reach statistical significance

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