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Circ Res 86(2):E36E41 Higman DJ et al (1996) Smoking impairs the activity of endothelial nitric oxide synthase in saphenous vein

The infiltrated immune cells then accumulate oxidized lipids to become foam cells and form atherosclerotic plaques

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The authors further demonstrated that, in contrast to FMD, nitrate-induced endothelium-independent vasodilation was not impaired

Smoking tobacco damages your heart and blood vessels (cardiovascular system)
