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effects tobacco has on the brain How Nicotine Affects and Why Nicotine Addiction Occurs Smoking lights up brain's response
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Please read Williams (2001)

2 examined 416 male construction workers in Chennai, India, and found a significant link between nicotine dependence and symptoms of anxiety and depression

Colonists would use tobacco to pay for essential natural resources, and in some areas, it was also used to pay taxes, fines, and the occasional marriage licence

Lennon, L

The monopoly heightened the exploitation of the Filipinos under the pretext of religion and obedience to the Spanish crown as it also aroused hostility among the people
