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Anti-citrullinated protein antibodies, smoking and other autoimmune diseases Anti-CCPs are highly specific for RA, but they are found in 5 to 13% of patients with psoriatic arthritis [78] and also a minority of patients with primary Sjgren syndrome have an elevated anti-CCP titer, which is linked to the presence of synovitis [79]

The adverse effects of nicotine in the hepatic system include the upregulation of inflammatory cytokines, the development of secondary polycythemia, and blockage of proliferation and activation of apoptosis in lymphocytes

And for those who are facing problems, smoking promises their quick resolution and the beginning of a bright streak in life.