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Chi-square test or Fisher's exact probability will be used to compare the incidence of adverse events between the two groups, and rank sum test will be used to compare the severity of adverse events

Studies show that smokers have a higher infertility rate than nonsmokers

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A person should seek medical advice if they experience: severe symptoms, such as pain, a high fever, or difficulty breathing swelling that lasts longer than 2 weeks additional symptoms, such as night sweats and a persistent fever swelling with no other symptoms, which may be a sign of cancer or an autoimmune disease a hard and painless swelling in the lymph node a rapid change in the size of the lymph node swelling in more than one area of lymph nodes, such as in the neck and the groin Swollen cervical lymph nodes are common