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CYP1A1 metabolic activity has also been shown to be increased by approximately 66%70% in smokers, mainly due to exposure to aryl hydrocarbons such as benzo [a]pyrene (Vistisen, Loft, and Poulsen, 1991)

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The researchers speculated that the advanced aging characteristics displayed by smokers were caused by the toxins contained in cigarettes, toxins that can speed up the breakdown of collagen (the protein fibers that give skin its elasticity and strength)

doi: 10.1016/0029-7844(94)00381-M
