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We then measured the levels of IL-1, G-CSF, IL-10, IL-13, IL-17, MIP-1, VEGF, IFN, IL-12, IFN, IL-1RA, TNF, IL-4 and IL-8 using Luminex beads, and IL-6 via mesoscale analysis

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In turn, ROS and pro-inflammatory mediators such as IL-6 and IFN have been reported to increase chemotherapy resistance by up-regulating anti-apoptotic genes, stimulating stemness, increasing repair of damaged DNA, and increasing drug efflux 29,41,63