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The vast number of data-poor new and existing inhalable substances, including ambient or occupational exposure-related chemicals/substances, pharmaceuticals, and consumer and commercial products, as well as mixtures of different substances, and repeated exposure scenarios precludes the feasibility of using traditional in vivo animal studies to evaluate the potential adverse effects of these exposures and scenarios (National Research Council, 2007)

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These include blood clots, coronary heart disease, heart attacks, certain types of cancer, and lung disease

A meta-analysis of the efficacy of over-the-counter nicotine replacement, Tobacco Control 2003

oxygen bleach or chlorine bleach Burning cigarette ashes are capable of scorching fabric fibers and producing dark burn marks on fabric