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RNO also reversed the downregulation of epithelial markers (E-cadherin, ZO-1, and KRT5) in HBECs

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14 National and local policies The Tobacco Free Lancashire & South Cumbria Strategy 2023-2028 (1887 KB) has been developed in line with the Tobacco Control Plan for England, and building on the previous strategy by setting out the ambition to achieve a smokefree generation by: preventing children from taking up smoking in the first place - making smokefree the new normal stamping out inequality, for example smoking in pregnancy supporting smokers - especially those who are parents - to quit work towards reducing the uptake of vaping among children and young people Further information about the authorities' response to smoking and tobacco use can also be found on the Blackpool JSNA Smoking page