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Doppler Ultrasound and Clinical Observations Exposure to active smoking affects the systole/diastole (S/D) flow velocity ratio (S/D) in the fetal UA and the middle cerebral artery (MCA), as revealed from Doppler sonography ultrasound examinations (Albuquerque et al., Clinical ultrasound studies also show structural changes in the umbilical cord in pregnancies complicated by IUGR: the size of the Wharton's jelly is increased (101.60 37.75 in the smoking IUGR group vs

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