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6 However, since July 2019, a rapid increase in severe pulmonary disease associated with vaping 7 (EVALI) has called the relative harm of e-cigarettes into question

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The multiple health hazards that have been associated with smoking addiction have raised the need for safe and effective treatments able to facilitate smoking cessation
It has been shown to be cardiotoxic in overdose and should be considered as a cause in patients with unexplained widening of the QRS complex in the electrocardiograph (Curry et al 2005)

*Correspondence: Giulia Di Benedetto, [email protected] These authors have contributed equally to this work These authors share senior authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
