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[5] The family name Newhart is of German origin ( Neuhart )

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After 18 days of tobacco leaf fermentation (Figure 5A), a total of 854 differential metabolites were screened in the comparison between CK and DX, among which 345 were up-regulated and 509 were down-regulated, in the comparison between CK and BLS, a total of 793 differential metabolites were screened, among which 258 were up-regulated and 535 were down-regulated, in the comparison between CK and DX_BLS, a total of 862 differential metabolites were screened, among which 324 were up-regulated and 538 were down-regulated, in the comparison between DX and BLS, a total of 888 differential metabolites were screened, among which 419 were up-regulated and 469 were down-regulated, in the comparison between DX and DX_BLS, a total of 660 differential metabolites were screened, among which 286 were up-regulated and 374 were down-regulated, in the comparison between BLS and DX_BLS, a total of 889 differential metabolites were screened, among which 456 were up-regulated and 433 were down-regulated