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Device modifications, such as increasing the heat to allow the device to burn more e-liquid, expose users to more toxicant emissions, increasing the danger to users without decreasing the addictive potential, according to the authors

[126] found that CS exposure in mice and CSE exposure in bronchial epithelial cells could induce EMT by activating the Akt signaling pathway

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E-cigarette, or Vaping, Product Use-Associated Lung Injury (or EVALI) is a serious lung disease linked to vaping devices, primarily THC-containing products from informal or black-market sources