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Major hormones that get disturbed by smoking are: Thyroid hormones Testosterone Estrogen Follicle-stimulating hormone Luteinizing hormone Cortisol Prolactin These hormonal imbalances contribute to various health problems like early menopause, menstrual cycle irregularities, diabetes, sleep issues and acne

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Dopamine is a hormone associated with feelings of pleasure and reward, so when alcohol and nicotine are consumed together, they can increase each others effects on these reward pathways which can intensify the pleasurable sensations experienced

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Nicotinic membrane receptors on cough sensors