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Methods In order to calculate the absolute increase in lifetime cancer risk (AR) resulting from consumption of ten units of alcohol (one bottle of wine) or ten cigarettes per week we began by subtracting the sum of the Alcohol Attributable Fraction (F AA ) (Alcohol Attributable Fraction for England 2013) [21] for all known alcohol-related cancers and Tobacco Attributable Fractions (F TA ) (Tobacco-attributable cancer burden in the UK) [22] for all tobacco-related cancers from the overall lifetime risk (R 0 ) of cancer (Cancer Research UK (CRUK) 2010) [23] for the general population (Additional file 1: Table S2)

People who smoke between one and 14 cigarettes daily had 21-fold higher risk of dying from chronic lung disease, 13-fold higher for lung cancer, and 2-fold higher risk of dying from heart disease, compared to people who have never smoked

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13,15 More research is needed on the comparative efficacy among current treatment options
