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hence, they considered that it might be a possible mechanism that hepatocytes would differentiate into hepatoma cells, because the p53-dependent damaged DNA repairing pathway was blocked, and the functions of key tumor-suppressor genes of hepatocytes were abolished 56

Of the 46 remaining papers, four studies were excluded due to limitations found in the title or abstract

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 19902015: a systematic analysis for the global burden of disease study 2015

They compared three of them in this latest study

During that time, the researchers documented 125,000 deaths and 54,000 cardiovascular events such as heart attacks, strokes, and heart failure