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According to one article (here), ACS president LaSalle D

Good news is that quitting will make a big difference

A recent study of mice exposed to IQOS aerosol for six months observed increased markers for pulmonary emphysema similar to those in CS exposure, indicating that IQOS is not completely safe

On the other hand, in this study, the remaining smoking trajectory groups, including former smokers, new current smokers, and decreasing light smokers, had lower risks than the above two groups but higher risks than never smokers

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