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Together, the presence of these signatures in nonmalignant, chronically exposed cells supports the idea that long-term cigarette exposure acts both as a genotoxic insult and as a selective pressure favoring cells capable of enduring genomic stress 20,26,27

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Commercial Tobacco Use in American Indian and Alaska Native Populations Download and Print: Fact Sheet Additional Languages Many tribes use tobacco in a traditional way for ceremonial or medicinal purposes, such as healing ceremonies and offerings

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