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[55] Nicotine has a higher affinity for acetylcholine receptors in the brain than those in skeletal muscle, though at toxic doses it can induce contractions and respiratory paralysis

Cellular life within the leaves must be maintained for a certain period after harvest to allow residual cellular respiration to trigger advantageous chemical and biological transformations
In homeopathy, a very low dose of Nicotiana tabacum is also prescribed for migraines, nausea, vomiting and circulation problems
doi: 10.1016/j.neubiorev.2005.03.008

Central to FDA's work since that time has been evaluating how to address the D.C
