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A comprehensive review that examines the evidence for a role for DA-mediated transmission in signalling both aversive and emotionally salient, non-reward-related behavioural events

JAMA 289, 427 (2003)

Begg S., Vos T., Barker B., Stevenson C., Stanley L., and Lopez AD., (2007) The Burden of Disease and Injury in Australia 2003, PHE 82 Canberra: Australian Institute of Health and Welfare, p76

The research is, in my humble opinion, proof enough that at the very least it is a product less harmful than traditional smoking

Haywood Brown, professor of obstetrics and gynecology at Duke University School of Medicine, who was not involved in the new report