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"By the mid-1990s, the airlines came to understand that the vast majority of their passengers liked this change, which was funny because people thought that was impossible until it happened," Dobbins said

While it is not the only component in cigarette smoke responsible for throat discomfort, its effects on circulation and tissue recovery can contribute to ongoing, constant irritation

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In addition, PG with nicotine caused increased macrophage and CD4 + /CD8 + T-lymphocytes cell counts in BALF compared to air control, but these effects were ameliorated when animals were sub-chronically exposed to PG alone [42]