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In total, 51 studies contributed weight change data in participants under control conditions (untreated quitters)

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While it is generally unclear whether toxicity from e-cigarettes stems from higher nicotine concentrations or rapid delivery mechanisms, it is hypothesized that increased plasma concentration and higher bioavailability of nicotine, depending on the isomer of nicotine, make it faster to be absorbed into circulation, hence why its effects may be exaggerated

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Its not clear exactly how smoking leads to hair damage, but some possible mechanisms include: Oxidative stress Smoking may cause changes in your body that lead to inflammation and an increase in harmful free radicals that damage DNA, a phenomenon known as oxidative stress