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Reproduced 5 August 2010, ISBN 978-1176904705 "CPAA: Quit Smoking Campaign, Anti Tobacco & Quit Smoking Campaign"

That landmark report, along with subsequent Surgeon General reports on the addictive power of nicotine and the dangers of secondhand smoke, led to a sea change in the country's attitude toward tobacco

While this review summarizes the current evidence from preclinical and clinical studies, most of the existing findings are based on animal models or short-term use human studies, which may not fully reflect the consequences of regular use in humans

That article is about nicotine, not cannabis, but the practical takeaway still applies

This is the amount present in the tobacco before the cigarette is lit, but this figure does not reflect the whole picture