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Fine particulate matter, when inhaled, can travel all the way into the lungs air sacs where gas exchange takes place

Mechanically, p53 induced by DNA damage activates p21

Casella G, Caponnetto P, Polosa R: Therapeutic advances in the treatment of nicotine addiction: present and future

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There is growing consensus among scientific and clinical experts that use of e-cigarettes can help people who smoke to stop using known-deadly cigarettes
