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Some smokers, however, may experience withdrawal symptoms for several months

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The combination of high nicotine concentrations delivered efficiently to a physiologically vulnerable adolescent population raises significant concern for both acute events (in susceptible individuals) and the long term development of cardiovascular disease (10, 1214)

If smoking is gradually reduced , nicotine contributes to the release of hormones such as serotonin and dopamine and these symptoms subside says Dr Licia Syracuse, Oncologist and Coordinator at the Centre for Anti-Smoking at Humanitas
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