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An additional literature search was conducted to ensure the inclusion of the most up-to-date evidence, resulting in the selection of 16 RCTs.58, 108, 117, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198 The results showed that combination NRT group showed significantly increased smoking cessation success rates at six months or longer compared to the NRT monotherapy group (RR, 1.26

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