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There were similar rates of mild adverse events (e.g., nausea, restlessness, insomnia, irritability) across groups in trials of cytisine based on our initial overview.22 However, an updated Cochrane review on cytisine42 suggested there may be a small increase in adverse events, which could constitute a small harm (4 RCTs, n = 4052

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The percentage of men smoking has particularly declined since the early 21st century, from 43% in 2000
I could have cheekbone implants and even blow a bit of air out of a curled lip to express disapproval
