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Small clinical trials using nicotine transdermal patches in early-stage Parkinsons and mild cognitive impairment (MCI) have shown modest improvements in memory, attention, and motor symptoms, though larger trials are still needed

(2014) 9:e85077

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Third, we sought to provide enhanced structural-behavioral insight via emergent database driven meta-analytic tools, which allow for the characterization of typical patterns of task-based co-activation and associated behavioral phenomenon for user-specified seed regions of interest
