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Bupropion Bupropion is less effective than varenicline or combined NRT
However, the extent of their impact can differ based on the population under study and the methodologies employed in the research (37,38)

His leg is almost totally paralyzed yet he refused to use a wheelchair and insisted on using a walker and wanted a cane even though sometimes his legs buckled under him

Those prone to anxiety or panic disorders may find that nicotines stimulatory effects intensify restlessness, palpitations, or panic episodes
