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The results of these studies indicate a significant variability in the nicotine delivery from differing devices, with some not increasing plasma nicotine concentrations significantly [59] and some delivering nicotine at a level approaching that of a tobacco cigarette [62]

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Nicotine is more addictive physiologically in our brain than even cocaine or heroin is, said Russell Buhr, MD, PhD, a pulmonologist at UCLA Health who also runs an outpatient practice in Westwood

Among these, nicotine is the primary addictive component

To the left of the mirror it reads, "Thank You" in white lettering against a maroon background