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Youth Lung Vulnerability: Researchers note that starting smoking at a young age likely increases the risk of respiratory symptoms because the lungs are still developing, making them more susceptible to tobacco smoke damage

Additionally, a calcitriol-elicited downregulation of the anti-apoptotic BCL2 and BCLXL and overexpression of the pro-apoptotic BAX, BAK , and BAD genes have also been described [147]

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