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It has been reported that plasminogen activator inhibitor-1 gene expression in endothelial cells and vascular remodeling are normalized by ROCK inhibitor treatment in atherosclerosis models [83, 84]

The TRL policy should detail the penalties for violations, including a graduated system of penalties, starting with fines and escalating to license suspension or revocation for repeated offenses

There was no need for props because tobacco companies lined up to sponsor TV shows ( The Flintstones' first season on ABC was sponsored by Winston cigarettes), and paid hefty sums for strategic movie placement and celebrity endorsements

It is well known that nicotine is extremely addictive and has a multitude of harmful effects

10.1016/j.neubiorev.2016.03.017 88
