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Studies of the effects of maternal smoking of conventional cigarettes during pregnancy, coupled with preclinical literature examining the effects of maternal self-administration of nicotine during pregnancy, suggest that e-cigarette use by mothers during pregnancy presents a wide variety of risks to fetal, infant, and child brain development

Dudish SA, Pentel PA, Hatsukami DK (1996)

Smoking affects your body by: raising your blood pressure and heart rate lowering oxygen levels in your blood reducing blood flow to your heart and brain increasing the risk of blood clots damaging your arteries weakening the walls of your arteries, increasing the risk of an aneurysm (bulging blood vessel) harming your lungs and making breathing harder increasing the risk of chronic lung disease, such as chronic obstructive pulmonary disease (COPD) increasing the risk of poor blood flow to your legs lowering good cholesterol and raising triglycerides