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Nicotine can cause health problems, such as irregular heart rhythm and heart rate changes

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In addition, within the adolescent M1, maladaptive changes in 5-HT signaling and 5-HT 1A activity after nicotine or fluoxetine exposure may potentiate hyper-responsiveness to dopaminergic drugs and prime adolescent vulnerability for future substance abuse

And e-cigarettes don't necessarily deter young people from smoking tobacco, according to a study from the Centers for Disease Control and Prevention published Monday