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But we cant simply use the way a plant looks to predict how it will affect the body and mind, says neuroscientist Nick Jikomes, previously the director of science and innovation at the cannabis e-marketplace Leafly

So how, at age 32, did he suddenly become one of its greatest advocates

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At the same time, it also activates nicotinic acetylcholine receptors in the brain and appears to cause a release of both dopamine and endogenous opioids, which activate opioid pathways in the neural reward system, producing feelings of pleasure and contributing to its reinforcing effects