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Inhal Toxicol, 2018

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As the available evidence is still limited, this review focuses on these diseases while placing particular emphasis on the molecular mechanismssuch as modulation of inflammatory pathways, promotion of weight loss, strengthening of antioxidant defense against reactive oxygen species (ROS), and alterations in the gut microbiotawhich may provide broader insights into the potential effects of KD on skin health (14, 1820)

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Shaik et al.s experiments have shown that SLT users (gutkha and khaini users) had significantly higher oxidative stress marker levels than nonusers [138]