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Epigenetic changes include aberrant DNA methylation, histone modifications and variants, microRNA (miRNA) deregulation, chromatin remodeling, and nucleosome positioning [221, 224, 225]
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In practice, this could mean that over a given year, a smoker living in Tobacco Nation could be inhaling over 500 more cigarettes than the average smoker in the rest of the U.S
8 As is reflected in the examination of the Cigar Factory Strike, these are not new problems faced by the working class
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