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Leading Causes of Death, 1900-1998

Rates for smokers are about 60 percent higher than for non-smokers

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In summary, compelling experimental evidence indicates e-cig as an important factor to promote metastasis by inducing epithelial-mesenchymal transition (EMT), enhancing cancer cell stemness and plasticity, and increasing lymphangiogenesis, all of which facilitate tumor cell dissemination to distant sites