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The causal chain of events linking smoking to inflammation To answer the second question, let us consider the causal chain of events linking smoking to lung inflammation: Emission of toxicants leads to exposure to toxicants, which in turn leads to lung inflammation A reduction in toxicant emission should, therefore, lead to a reduction in exposure to toxicants, which in turn should lead to a reduction in lung inflammation

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For example, Canada has detailed lists of specific ingredients that are allowed, and Belgium has restrictions on any cooling activity in tobacco products